BDBM50024210 1H-indole-3-ethanamine::2-(1H-indol-3-yl)ethanamine::2-(3-indolyl)ethylamine::CHEMBL6640::tryptamine

SMILES NCCc1c[nH]c2ccccc12

InChI Key InChIKey=APJYDQYYACXCRM-UHFFFAOYSA-N

Data  74 KI  2 IC50  3 Kd  6 EC50

PDB links: 13 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50024210   

Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50024210(1H-indole-3-ethanamine | 2-(1H-indol-3-yl)ethanami...)
Affinity DataKi:  36nMAssay Description:Binding affinity for recombinant human 5-hydroxytryptamine 1D receptor beta was determined using [3H]-5-HT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50024210(1H-indole-3-ethanamine | 2-(1H-indol-3-yl)ethanami...)
Affinity DataKi:  86nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50024210(1H-indole-3-ethanamine | 2-(1H-indol-3-yl)ethanami...)
Affinity DataKi:  525nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50024210(1H-indole-3-ethanamine | 2-(1H-indol-3-yl)ethanami...)
Affinity DataKi:  1.02E+4nMAssay Description:Binding affinity (Ki) to rat cortical membranes at 5-HT1B binding site by using [125 I] ICYP as a radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed